Shell up to 49 mm in length with large, rounded protoconch of 1.5 whorls and weakly shouldered, broad teleoconch whorls. Axial sculpture of last teleoconch whorl consisting of 3 narrow, high, rounded, frondose, weakly or moderately webbed varices, each with short, frondose, open primary spines and few, narrower secondary spines. Other axial sculpture of 1 or 2 strongly nodose, high intervarical ribs. Spiral sculpture of strong, high primary cords of approximately same strength and smaller secondary cords. Spiral sculpture of subsutural ramp of last whorl with adis and IP, followed by P1, s1, P2, s2, P3, s3, P4, s4, P5, s5, P6, s6 and additional, tertiary cords and narrow threads. Aperture broadly ovate. Columellar lip smooth. Outer lip erect, denticulate, Urate within. Siphonal canal moderately long, broad, narrowly open, weakly dorsally bent, with 3 fromdose ADP, MP, and ABP spines. ADP weakly dorsally bent. Ochre with some brown maculations on shoulder, varices and spiral sculpture.
Radula somewhat atypical for a Chicomurex species with obviously less crowded rows of teeth.

Chicomurex protoglobosus differs from all other species of Chicomurex except C. rosadoi in having a large and globose protoconch, indicating intracapsular larval development. Chicomurex rosadoi is endemic to Mozambique and closely adjacent areas and also has a broad, globose protoconch. denoting the same kind of larval development. Chicomurex turschi has a small, rounded, paucispiral protoconch, and shell with 4.25 teleoconch whorls like the holotype of C. protoglobosus are only 13 or 14 mm in length. Judging from its paucispiral protoconch. C. protoglobosus is probably endemic to the New Caledonian area. It was described from a single, subadult specimen but since its discovery a few adult specimens were collected in 250-400 m.

Distribution. Indo-W. Pac. (P). New Caledonia, in 250-400 m.